The aim of the project is to identify the best biological way to control Cactus Cochineal 'Dactylopius opuntiae' and convince local authorities and farmers in the adoption of the suggested methodologies. For this reason both research and training aspects will be involved. In fact, after an initial phase of discovery and proof of concepts, the best Integrated Pest Management strategies identified will be widespread thanks to stakeholder contribution. The achievement of results will be possible also thanks to genetic effort, by import of resistant eco-type in vitro plant and evaluating their resistance to the cochineal, under laboratory and cage conditions. Therefore, by sustainable and efficient techniques, is expected to limit the spread of Dactylopius opuntiae in short period and good level of stability in ecological diversity over the years